Childhood Nephrotic Syndrome Complicated by Catastrophic Multiple Arterial Thrombosis Requiring Bilateral Above-Knee Amputation

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[Arterial thrombosis in the nephrotic syndrome].

It is not common knowledge that, besides venous thrombosis, arterial thrombotic events may also be associated with the nephrotic syndrome. Two patients are reported who were admitted because of thrombotic occlusions in the peripheral arteries and developed nephrotic syndrome due to membranous glomerulonephritis after various lapses of time. These two cases and the literature support the hypothe...

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Knee disarticulation versus above-knee amputation.

If below-knee amputation is impossible, knee disarticulation should be considered before above-knee amputation, regardless of age and etiology. Knee disarticulation which leaves the femur and patella untoched offers many advantages. The surgical technique is simple and non-traumatic since no bone or muscle tissue is to be dissected. The thigh muscles are completely preserved and thus there is n...

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Knee Fusion or Above-The-Knee Amputation after Failed Two-Stage Reimplantation Total Knee Arthroplasty

Prosthetic joint infection (PJI) is a serious complication of total knee arthroplasty (TKA). Control of infection after a failed two-stage TKA is not always possible, and the resolution of infection may require an above-knee amputation (AKA) or a the-knee (KF). The purpose of this review is to determine which treatment method (AKA or KF) yields better function and ambulatory status for patients...

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Nephrotic syndrome complicated by tubular dysfunction .

Introduction Abnormalities of proximal renal tubular function in the nephrotic syndrome are rare but well documented (Bruck, Rapoport and Rubin, 1954; Kovnat and Lin, 1974; Pabico et al., 1976), particularly in children. The mechanisms underlying this combination remain obscure; a number have been proposed (Vitacco et al., 1970) including the recent speculation that a common mechanism linked by...

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ژورنال

عنوان ژورنال: Frontiers in Pediatrics

سال: 2020

ISSN: 2296-2360

DOI: 10.3389/fped.2020.00107